Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623770 | 1.00 | LTA4H (0.56) | LTA4HPDE2AJAK2JAK1JAK3 | |
| SCHEMBL28619739 | 0.84 | LTA4H (0.49) | LTA4HMLNRTACR1DRD4 | |
| SCHEMBL28619738 | 0.84 | LTA4H (0.49) | LTA4HMLNRTACR1DRD4 | |
| SCHEMBL8123690 | 0.77 | LTA4H (0.52) | LTA4HPOLB | |
| SCHEMBL31535374 | 0.73 | LTA4H (0.62) | LTA4HTACR1DRD4 | |
| SCHEMBL28609586 | 0.73 | TP53 (0.39) | LTA4HJAK2JAK1JAK3MLNR | |
| SCHEMBL28609587 | 0.73 | TP53 (0.39) | LTA4HJAK2JAK1JAK3MLNR | |
| SCHEMBL28612840 | 0.72 | POLB (0.39) | POLB | |
| SCHEMBL28612839 | 0.72 | POLB (0.39) | POLB | |
| SCHEMBL28622416 | 0.72 | LTA4H (0.33) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072546-B | Five-membered heteroaromatic derivative and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-113072546-A | Five-membered heteroaromatic derivative and preparation method and application thereof | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |