Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18690622 | 0.91 | RXRA (0.46) | SMN1; SMN2GAAKDM4EMRGPRX4CA12 | |
| SCHEMBL17958070 | 0.86 | PTPN11 (0.48) | CA12CA1CA2CA9IDO1 | |
| SCHEMBL18165160 | 0.86 | CA12 (0.47) | MRGPRX4CA12CA1CA2CA9 | |
| SCHEMBL13166235 | 0.86 | KDM4E (0.46) | GAAKDM4ECA12CA1CA2 | |
| SCHEMBL3453194 | 0.86 | IDO1 (0.60) | SMN1; SMN2KDM4ECA12CA1CA2 | |
| SCHEMBL15573936 | 0.85 | TSHR (0.56) | MRGPRX4CA12CA1CA2CA9 | |
| SCHEMBL926919 | 0.85 | RAB9A (0.49) | CA12CA1CA2CA9IDO1 | |
| SCHEMBL21601440 | 0.85 | AAK1 (0.49) | SMN1; SMN2GAAKDM4ECA12CA1 | |
| SCHEMBL21601370 | 0.84 | SCN9A (0.48) | SMN1; SMN2GAAKDM4ECA12CA1 | |
| SCHEMBL4007583 | 0.84 | CA12 (0.50) | SMN1; SMN2GAAKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113173891-A | Molecular probe derived from calcium-sensitive receptor protein antagonist and application of molecular probe in parathyroidectomy | 大连医科大学附属第二医院 | 2021-07-27 | — | — | CN | disclosed |