Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13903978 | 0.99 | TGM2 (0.53) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| Water SCHEMBL9650629 | 0.97 | TGM2 (0.52) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4995421 | 0.97 | TGM2 (0.52) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| Bromide SCHEMBL14637403 | 0.93 | ZDHHC20 (0.45) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL28669293 | 0.92 | TGM2 (0.48) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL6472879 | 0.92 | TGM2 (0.48) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16319751 | 0.92 | ZDHHC20 (0.46) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL17083922 | 0.90 | TGM2 (0.49) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28671813 | 0.89 | TGM2 (0.48) | TGM2DNM1KMT2AMEN1SMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL16108733 | 0.88 | TGM2 (0.47) | TGM2DNM1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109070025-B | Method and device for preparing aqueous polymer solution | 巴斯夫欧洲公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-113166050-A | Method for producing organic tellurium compound and method for producing vinyl polymer | 大塚化学株式会社 | 2021-07-23 | — | — | CN | disclosed |