Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007532 | 0.88 | LMNA (0.42) | LMNACA12CA1CA2CA7 | |
| SCHEMBL17440686 | 0.82 | ERN1 (0.44) | LMNAPRKDCCA12CA1CA2 | |
| SCHEMBL28468160 | 0.80 | ERN1 (0.38) | LMNAPOLBERN1DPP4ALDH1A1 | |
| SCHEMBL17440697 | 0.78 | NPC1 (0.52) | LMNAPOLBALDH1A1 | |
| SCHEMBL20607956 | 0.77 | MAOB (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31550130 | 0.77 | ALDH1A3 (0.41) | LMNAPRKDCERN1ALDH1A1KAT6A | |
| SCHEMBL28863844 | 0.75 | LMNA (0.34) | LMNAPRKDCKAT6ANQO1 | |
| SCHEMBL17543789 | 0.74 | NQO1 (0.44) | LMNANQO1PTGS2TSHR | |
| SCHEMBL16269517 | 0.73 | LMNA (0.51) | LMNAPOLBERN1ALDH1A1TSHR | |
| SCHEMBL29447891 | 0.72 | TSHR (0.42) | LMNACA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556244-B | Fused ring compound, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2021-09-03 | — | — | CN | disclosed |