Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 3/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.41 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28622745 | 0.86 | NOD1 (0.57) | NOD1PARP1NOD2TEKACVR1 | |
| SCHEMBL6921163 | 0.77 | TEK (0.59) | PARP1TEKMAPKAPK2ACVR1KDR | |
| SCHEMBL28128312 | 0.73 | PARP1 (0.59) | PARP1MAPKAPK2ACVR1 | |
| SCHEMBL4141791 | 0.71 | IP6K1 (0.52) | PARP1IP6K1IP6K3 | |
| SCHEMBL4141934 | 0.71 | SLC2A1 (0.54) | PARP1ACVR1IP6K1IP6K3 | |
| SCHEMBL4148739 | 0.71 | PARP1 (0.51) | PARP1ACVR1IP6K1IP6K3 | |
| SCHEMBL28619439 | 0.71 | NOD1 (0.68) | NOD1NOD2 | |
| SCHEMBL17797037 | 0.70 | DCLRE1B (0.56) | KDRGPR35KMODHODH | |
| SCHEMBL17796982 | 0.70 | DCLRE1B (0.53) | KDRGPR35KMODHODH | |
| SCHEMBL31585756 | 0.70 | DCLRE1B (0.53) | KDRGPR35KMODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354590-A | Quinazolinone compound for antagonizing NOD1/2 receptor signal pathway | 宁波康柏睿格医药科技有限公司 | 2021-09-07 | — | — | CN | disclosed |