⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022550 | 0.81 | TDP1 (0.30) | — | |
| SCHEMBL8022546 | 0.81 | TDP1 (0.30) | — | |
| SCHEMBL387501 | 0.80 | — | — | |
| SCHEMBL16864348 | 0.78 | — | — | |
| SCHEMBL16281819 | 0.78 | — | — | |
| SCHEMBL385510 | 0.76 | TSHR (0.36) | — | |
| SCHEMBL15084271 | 0.75 | — | — | |
| SCHEMBL13349106 | 0.74 | CTSL (0.31) | — | |
| SCHEMBL11662749 | 0.74 | FAAH (0.43) | — | |
| SCHEMBL11662752 | 0.74 | FAAH (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114786658-A | Use of KV7 potassium channel openers for the treatment of pain | 泽农医药公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-113365626-A | Method of treating pain with thiazoline anti-hyperalgesic drugs | 瑟赛治疗公司 | 2021-09-07 | — | — | CN | disclosed |