Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211458 | 0.96 | CPA3 (0.54) | CPA3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL21321975 | 0.87 | CPA3 (0.59) | CPA3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28212055 | 0.82 | CPA3 (0.61) | CPA3KEAP1FOLH1CPB2 | |
| SCHEMBL28211994 | 0.80 | CPA3 (0.44) | CPA3FOLH1 | |
| SCHEMBL7350860 | 0.77 | CPA3 (0.71) | CPA3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28092472 | 0.77 | HDAC3 (0.47) | CPA3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28211436 | 0.76 | FOLH1 (0.44) | MAPK1FOLH1 | |
| SCHEMBL28616838 | 0.75 | CPA3 (0.44) | CPA3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL18636728 | 0.74 | CPA3 (0.50) | CPA3FOLH1FFAR1 | |
| SCHEMBL28615243 | 0.74 | NAALAD2 (0.50) | CPA3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113453720-A | Double-ligand drug couplet and application thereof | 同宜医药（苏州）有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-108514646-B | Compounds for positron emission tomography | 恩多塞特公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-108514646-A | Compounds for positron emission tomography | 恩多塞特公司 | 2018-09-11 | — | — | CN | disclosed |
| CN-105849568-B | Compounds for Positron Emission Tomography | 恩多塞特公司 | 2018-05-04 | — | — | CN | disclosed |