Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.71 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1857365 | 0.90 | CYP1A2 (0.61) | CPA3KEAP1FOLH1CYP1A2CPA1 | |
| SCHEMBL3223107 | 0.89 | HDAC3 (0.61) | CPA3KEAP1HDAC3MAPK1ADRA1A | |
| Water SCHEMBL4010621 | 0.88 | CYP1A2 (0.59) | CPA3FOLH1CYP1A2CPA1 | |
| SCHEMBL21321975 | 0.87 | CPA3 (0.59) | CPA3KEAP1HDAC3MAPK1ADRA1A | |
| SCHEMBL8775151 | 0.86 | MAPT (0.64) | CPA3KEAP1HDAC3MAPK1ADRA1A | |
| SCHEMBL12145183 | 0.86 | GRM3 (0.68) | CPA3FOLH1CPA1 | |
| SCHEMBL12291701 | 0.85 | FOLH1 (0.58) | CPA3FOLH1CPA1 | |
| SCHEMBL7427004 | 0.84 | L3MBTL1 (0.54) | CPA3ADRA1ASLC6A3HDAC1HDAC2 | |
| SCHEMBL7365950 | 0.84 | L3MBTL1 (0.54) | CPA3ADRA1ASLC6A3HDAC1HDAC2 | |
| SCHEMBL7439254 | 0.84 | CPA3 (0.56) | CPA3KEAP1HDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050850-A1 | 1-Carboxyalkanoylindolin-2-carboxylic acids and derivatives thereof, processes for their preparation, and pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1982-05-05 | — | — | EP | disclosed |