SCHEMBL2862449

SCHEMBL2862449

COC(=O)C(Cl)CCCCC(Cl)C(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
BIRC2 Q13490 5/20 0.37
ABCB1 P08183 1/20 0.35
TSHR P16473 2/20 0.35
ALDH1A2 O94788 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALDH2 P05091 1/20 0.34
ALDH1A3 P47895 1/20 0.34
USP2 O75604 1/20 0.34
LMNA P02545 1/20 0.34
CA14 Q9ULX7 2/20 0.33
CA12 O43570 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6758586 0.95 CA1 (0.43) ZDHHC7CA1CA2SMN1; SMN2BIRC2
SCHEMBL4403214 0.91 ZDHHC7 (0.58) ZDHHC7CA1CA2BIRC2ABCB1
SCHEMBL7970891 0.91 ZDHHC7 (0.40) ZDHHC7CA1CA2SMN1; SMN2BIRC2
SCHEMBL2862400 0.90 SMN1; SMN2 (0.42) ZDHHC7CA1CA2SMN1; SMN2BIRC2
SCHEMBL11435375 0.89 ZDHHC7 (0.61) ZDHHC7CA1CA2BIRC2ABCB1
SCHEMBL11440159 0.89 ZDHHC7 (0.61) ZDHHC7CA1CA2BIRC2ABCB1
SCHEMBL11693502 0.89 ZDHHC7 (0.43) ZDHHC7CA1CA2SMN1; SMN2BIRC2
SCHEMBL28468724 0.89 ZDHHC7 (0.61) ZDHHC7CA1CA2BIRC2ABCB1
SCHEMBL11877076 0.89 ZDHHC7 (0.43) ZDHHC7CA1CA2SMN1; SMN2BIRC2
SCHEMBL10911418 0.89 ZDHHC7 (0.61) ZDHHC7CA1CA2BIRC2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
CN-1984981-B Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO 2010-11-17 CN disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
CN-1984981-A Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO (JP) 2007-06-20 CN disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed