SCHEMBL2862400

SCHEMBL2862400

COC(=O)C(Cl)CCC(Cl)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
ZDHHC7 Q9NXF8 1/20 0.39
CA14 Q9ULX7 2/20 0.36
TSHR P16473 3/20 0.35
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CA12 O43570 1/20 0.33
MME P08473 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
ALDH1A2 O94788 1/20 0.32
ALDH2 P05091 1/20 0.32
ALDH1A3 P47895 1/20 0.32
MGAM O43451 2/20 0.32
GAA P10253 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862449 0.90 ZDHHC7 (0.45) SMN1; SMN2CA1CA2ZDHHC7CA14
SCHEMBL6758586 0.90 CA1 (0.43) SMN1; SMN2CA1CA2ZDHHC7CA14
SCHEMBL508118 0.87
SCHEMBL11274815 0.87
SCHEMBL7066443 0.87
SCHEMBL6943569 0.85
SCHEMBL6943574 0.85
SCHEMBL10733705 0.84 CA2 (0.59) CA1CA2ZDHHC7TSHRBIRC2
SCHEMBL7976135 0.84 CA1 (0.39) SMN1; SMN2CA1CA2ZDHHC7CA14
SCHEMBL6546684 0.84 FOLH1 (0.42) SMN1; SMN2CA1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304693-B Modified resin, preparation method and application thereof in recycling ethylene glycol in polyester separation process 中国石油化工股份有限公司 2024-07-23 CN claimed
CN-115304693-B Modified resin, preparation method and application thereof in recycling ethylene glycol in polyester separation process 中国石油化工股份有限公司 2024-07-23 CN disclosed
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
CN-1984981-B Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO 2010-11-17 CN disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
CN-1984981-A Lubricating oil additive containing acrylic polymer and lubricating oil composition KURARAY CO (JP) 2007-06-20 CN disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed
US-6716918-B2 ATOM TRANSFER RADICAL POLYMERIZATION IN THE PRESENCE OF A REDOX CATALYST OF A TRANSITION METAL COMPLEX ALSO USING AN ORGANOHALOGEN OR HALOGENATED SULFONYL COMPOUND AS A POLYMERIZATION CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 2004-04-06 US disclosed
US-20020156196-A1 Methacrylate-based polymer and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-10-24 US disclosed
EP-0387725-B1 Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters SUMITOMO SEIKA CHEMICALS (JP) 1997-01-22 EP disclosed
EP-0719774-A1 A method for production of dibenzoxazolyl thiophenes SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-07-03 EP disclosed
US-5310940-A Sulfiding, cyclization SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1994-05-10 US disclosed
US-5221749-A Reacting a thiophene,2,5-dicarboxylic acid diester with a 2-aminophenol in the presence of an acid catalyst SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1993-06-22 US disclosed
EP-0387725-A2 Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1990-09-19 EP disclosed