Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.49 |
| ▸ | PI4KA | P42356 | 5/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.49 |
| ▸ | SCN4A | P35499 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101727 | 1.00 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL11837560 | 0.84 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL31385162 | 0.82 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL142514 | 0.82 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL113955 | 0.80 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL13780339 | 0.79 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL3113690 | 0.77 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL9762807 | 0.77 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL8656868 | 0.76 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL17507167 | 0.76 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109011-B | Benzothiazole compound, preparation method and application | 河北师范大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115109011-A | Benzothiazole compound, preparation method and application | 河北师范大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-108715589-B | Coumarin derivative used as caspase-3 activator and application thereof | 华侨大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-109265453-A | It is a kind of as the semicarbazones analog derivative of caspase-3 activator and its application | 华侨大学 | 2019-01-25 | — | — | CN | disclosed |