Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | AXL | P30530 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | PI4KA | P42356 | 3/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.51 |
| ▸ | SCN4A | P35499 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780339 | 0.85 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL3113690 | 0.84 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL28625232 | 0.82 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL30101727 | 0.82 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL785395 | 0.82 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL1913552 | 0.82 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL142514 | 0.82 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL27899294 | 0.82 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL11837560 | 0.81 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MAPTAXL | |
| SCHEMBL5164106 | 0.79 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2MAPTAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119035-A | RIPK1 kinase target inhibitor and preparation method and application thereof | 中山大学 | 2024-12-13 | — | — | CN | disclosed |