Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245622 | 0.89 | KMT2A (0.58) | KMT2ALMNATDP1CYP19A1CYP17A1 | |
| SCHEMBL27400293 | 0.82 | ALDH1A1 (0.55) | KMT2ALMNATDP1ALDH1A1MAPT | |
| SCHEMBL28979662 | 0.82 | HDAC1 (0.65) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL28596954 | 0.82 | HDAC1 (0.72) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL932927 | 0.82 | KMT2A (0.45) | KMT2ALMNATDP1CYP3A4ALDH1A1 | |
| SCHEMBL29557056 | 0.81 | KMT2A (0.51) | KMT2ALMNATDP1CYP19A1CYP17A1 | |
| SCHEMBL14351315 | 0.80 | KMT2A (0.53) | KMT2ALMNATDP1CYP19A1CYP17A1 | |
| SCHEMBL14351314 | 0.80 | KMT2A (0.53) | KMT2ALMNATDP1CYP19A1CYP17A1 | |
| SCHEMBL29556883 | 0.80 | KMT2A (0.53) | KMT2ALMNATDP1CYP19A1CYP17A1 | |
| SCHEMBL537263 | 0.79 | RECQL (0.56) | KMT2ALMNATDP1CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185454-A | Anthranilic acid amide compound based on entinostat skeleton and preparation and application thereof | 南华大学 | 2021-07-30 | — | — | CN | disclosed |