Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850677 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TRIM24TRIM33KDM4EPOLB | |
| SCHEMBL21570237 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TRIM24TRIM33KDM4EGAA | |
| SCHEMBL28897127 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TRIM24TRIM33RAB9ANPC1 | |
| SCHEMBL19964926 | 0.81 | TRIM24 (0.47) | ALDH1A1TRIM24TRIM33GAARAB9A | |
| SCHEMBL27257287 | 0.80 | MEN1 (0.46) | ALDH1A1SMN1; SMN2KDM4EGAAPOLB | |
| SCHEMBL28331384 | 0.79 | TRIM24 (0.48) | ALDH1A1TRIM24TRIM33GAARAB9A | |
| SCHEMBL8772644 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TRIM24TRIM33KDM4EPOLB | |
| SCHEMBL28590805 | 0.77 | KDM4E (0.46) | ALDH1A1SMN1; SMN2KDM4EGAAPOLB | |
| SCHEMBL29295631 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TRIM24TRIM33GAAPOLB | |
| SCHEMBL28641049 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TRIM24TRIM33SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429409-A | Sulfur-containing polysubstituted indolizine compound and preparation method thereof | 浙大城市学院 | 2021-09-24 | — | — | CN | disclosed |