Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31595886 | 0.85 | NAMPT (0.37) | NAMPTGDAHTR2CAKT1ENPP2 | |
| SCHEMBL30141445 | 0.84 | NAMPT (0.38) | NAMPTMMP8MMP3HTR2CAKT1 | |
| SCHEMBL29959822 | 0.78 | NAMPT (0.35) | NAMPTMMP8MMP3HTR2CAKT1 | |
| SCHEMBL17373227 | 0.74 | NR1H2 (0.40) | PARP1 | |
| SCHEMBL29640086 | 0.72 | HDAC2 (0.40) | CCNA2CDK2CCNA1PARP1 | |
| SCHEMBL13505458 | 0.72 | NAMPT (0.48) | NAMPTHTR2CAKT1ENPP2SCN9A | |
| SCHEMBL1994788 | 0.72 | NAMPT (0.38) | NAMPTHTR2CAKT1ENPP2SCN9A | |
| SCHEMBL12934637 | 0.71 | NAMPT (0.45) | NAMPTHTR2CAKT1ENPP2SCN9A | |
| SCHEMBL24229770 | 0.71 | NAMPT (0.47) | NAMPTHTR2CAKT1ENPP2SCN9A | |
| SCHEMBL11518308 | 0.71 | TMPRSS2 (0.42) | NAMPTHTR2CAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932919-B1 | JAK INHIBITOR COMPOUND AND USE THEREOF | HENAN MEDINNO PHARMACEUTICAL TECH CO LTD (CN) | 2024-06-26 | — | — | EP | claimed |
| CN-119591604-A | JAK inhibitor compounds and uses thereof | 迈英诺医药科技（珠海）有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2025036296-A1 | JAK INHIBITOR COMPOUND AND USE THEREOF | 迈英诺医药科技（珠海）有限公司 | 2025-02-20 | — | — | WO | disclosed |
| CN-117343063-A | Compounds as TRK inhibitors and/or RET inhibitors and uses thereof | 河南迈英诺医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-111606908-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |