Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 16/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 16/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 16/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 16/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 16/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 16/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 16/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 16/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645125 | 1.00 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28265446 | 0.78 | P2RX7 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28637947 | 0.78 | P2RX7 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28621729 | 0.73 | HDAC1 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28261748 | 0.73 | HDAC1 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28638771 | 0.73 | HDAC1 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6996836 | 0.72 | CA12 (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28660008 | 0.72 | HDAC2 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28621784 | 0.72 | HDAC2 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL20518391 | 0.69 | HDAC3 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997231-B | (E) Synthesis method of-configuration alkenyl ester triazole compound | 陕西师范大学 | 2021-09-21 | — | — | CN | disclosed |