SCHEMBL28625903

SCHEMBL28625903

Cc1cc(C(=O)OC2=CCCCC2)c(C)cc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 2/20 0.38
HSD17B10 Q99714 4/20 0.35
KDM4E B2RXH2 3/20 0.35
GAA P10253 3/20 0.35
HPGD P15428 2/20 0.35
RXRA P19793 2/20 0.34
GSTP1 P09211 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
CCR2 P41597 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20503234 0.78 KMT2A (0.47) ALDH1A1LMNACYP2C9MAPTHTT
SCHEMBL10663480 0.75 ALDH1A1 (0.33) ACMSDHSD17B10KDM4EGAAHPGD
SCHEMBL8140023 0.74 KDM4E (0.39) HSD17B10KDM4EGAAHPGDALDH1A1
SCHEMBL8138563 0.74 KMT2A (0.39) HPGDALDH1A1LMNAMAPT
SCHEMBL28334931 0.73 PPARA (0.40)
SCHEMBL30445691 0.73 KMT2A (0.44) ALDH1A1LMNACYP2C9MAPTHTT
SCHEMBL9824084 0.72 ALDH1A1 (0.34) HSD17B10KDM4EGAAHPGDRXRA
SCHEMBL27700768 0.72 GAA (0.38) ACMSDKDM4EGAARXRACCR2
Cyclohexene SCHEMBL28625904 0.71 KDM4E (0.42) HSD17B10KDM4EGAAHPGDRXRA
SCHEMBL3409037 0.71 HDAC4 (0.39) ACMSDHPGDGSTP1HCAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422612-B Synthetic method of aromatic hydrocarbon compound 中国科学院大连化学物理研究所 2021-08-10 CN disclosed