Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28641067 | 0.91 | MAPT (0.76) | MAPTTP53POLBALDH1A1HSD17B10 | |
| SCHEMBL28625763 | 0.91 | MAPT (0.62) | MAPTTP53POLBALDH1A1HSD17B10 | |
| SCHEMBL28621586 | 0.89 | POLB (0.53) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL28923060 | 0.83 | MAPT (0.50) | MAPTTP53POLBALDH1A1HSD17B10 | |
| SCHEMBL28630607 | 0.82 | MAPT (0.74) | MAPTTP53POLBALDH1A1HSD17B10 | |
| SCHEMBL28625832 | 0.81 | ALDH1A1 (0.60) | MAPTTP53POLBALDH1A1HSD17B10 | |
| SCHEMBL28636450 | 0.79 | POLB (0.53) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL28626506 | 0.79 | AKR1C3 (0.60) | MAPTTP53POLBMEN1KMT2A | |
| SCHEMBL4520996 | 0.77 | TP53 (0.56) | MAPTTP53RXFP1 | |
| SCHEMBL3952993 | 0.77 | TP53 (0.55) | MAPTTP53RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108715589-B | Coumarin derivative used as caspase-3 activator and application thereof | 华侨大学 | 2021-04-20 | — | — | CN | disclosed |