Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.68 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16237943 | 0.96 | HRH3 (0.69) | HRH3L3MBTL1MBTD1L3MBTL3SLC6A3 | |
| SCHEMBL4117753 | 0.86 | HRH1 (0.67) | HRH3L3MBTL1MBTD1L3MBTL3SLC6A3 | |
| SCHEMBL13649141 | 0.83 | HRH3 (0.68) | HRH3L3MBTL1MBTD1L3MBTL3SLC6A3 | |
| SCHEMBL2250341 | 0.82 | SIGMAR1 (0.60) | HRH3L3MBTL1MBTD1L3MBTL3SIGMAR1 | |
| SCHEMBL4689587 | 0.82 | HRH3 (0.71) | HRH3L3MBTL1MBTD1L3MBTL3SLC6A3 | |
| SCHEMBL14100544 | 0.82 | HRH3 (0.71) | HRH3L3MBTL1MBTD1L3MBTL3SLC6A3 | |
| SCHEMBL23682835 | 0.81 | L3MBTL1 (1.00) | HRH3L3MBTL1MBTD1L3MBTL3SLC6A3 | |
| 1-Phenethylpiperidine SCHEMBL9870299 | 0.81 | SIGMAR1 (0.62) | HRH3L3MBTL1MBTD1L3MBTL3SLC6A3 | |
| SCHEMBL17828190 | 0.80 | HRH3 (0.75) | HRH3L3MBTL1SIGMAR1 | |
| SCHEMBL13556830 | 0.80 | SPHK1 (0.63) | HRH3L3MBTL1MBTD1L3MBTL3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-28 | — | — | CN | disclosed |