Dimethylamine

Dimethylamine

SCHEMBL28626358

CNC.OC1Cc2ccccc21

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.43
KDM1A O60341 4/20 0.42
PDPK1 O15530 1/20 0.42
HTR2A P28223 2/20 0.41
HRH1 P35367 2/20 0.41
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2C P28335 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
KCNH2 Q12809 1/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12228571 0.91
SCHEMBL16870529 0.91 GRIN2D (0.45) KDM1AHTR2AGRIN2DGRIN3BGRIN1
SCHEMBL30968744 0.91
SCHEMBL12279944 0.78 RET (0.50) SIGMAR1HTR2AGRIN1GRIN2B
SCHEMBL29439854 0.76 HTR2A (0.55) SIGMAR1HTR2AHRH1GRIN1GRIN2B
SCHEMBL14477617 0.76 DRD2 (0.38) SIGMAR1HTR2AGRIN2DGRIN3BGRIN1
SCHEMBL14870745 0.76 HTR2A (0.55) SIGMAR1HTR2AHRH1GRIN1GRIN2B
SCHEMBL270201 0.75 KDM1A (0.40) KDM1AGRIN2DGRIN3BGRIN1GRIN2A
Cyclohexylamine SCHEMBL5849650 0.75 KDM1A (0.42) SIGMAR1KDM1A
SCHEMBL5190442 0.74 GRIN1 (0.40) SIGMAR1KDM1AGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113230374-A External formula for treating cold in uterus and preparation method and application thereof 湖南省国方中医药科技有限公司 2021-08-10 CN disclosed