SCHEMBL16870529

SCHEMBL16870529

OC1Cc2ccccc2C(O)Cc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.45
GRIN3B O60391 1/20 0.45
GRIN1 Q05586 1/20 0.45
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
GRIN2C Q14957 1/20 0.45
GRIN3A Q8TCU5 1/20 0.45
KDM1A O60341 4/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
HTR2A P28223 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30968744 1.00
SCHEMBL12228571 1.00
Dimethylamine SCHEMBL28626358 0.91 SIGMAR1 (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12279944 0.86 RET (0.50) GRIN1GRIN2BHTR2A
SCHEMBL14870745 0.83 HTR2A (0.55) GRIN1GRIN2BHTR2A
SCHEMBL29439854 0.83 HTR2A (0.55) GRIN1GRIN2BHTR2A
SCHEMBL14477617 0.83 DRD2 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL270201 0.83 KDM1A (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Cyclohexylamine SCHEMBL5849650 0.82 KDM1A (0.42) KDM1A
SCHEMBL5190442 0.81 GRIN1 (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828518-B2 Copolymer formulations, methods of manufacture thereof and articles comprising the same DOW GLOBAL TECHNOLOGIES LLC (US) 2017-11-28 US disclosed
US-20150184017-A1 COPOLYMER FORMULATIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2015-07-02 US disclosed