Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.53 |
| ▸ | DHODH | Q02127 | 6/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29742884 | 1.00 | PIM1 (0.53) | PIM1PTGER4DHODHXDHFFAR1 | |
| SCHEMBL29742939 | 0.86 | PTGER4 (0.54) | PTGER4THRATHRB | |
| SCHEMBL28626430 | 0.86 | PTGER4 (0.54) | PTGER4THRATHRB | |
| SCHEMBL29742912 | 0.84 | PTGER4 (0.61) | PTGER4 | |
| SCHEMBL29742860 | 0.80 | ALDH1A1 (0.48) | PIM1PTGER4XDH | |
| SCHEMBL28636888 | 0.80 | ALDH1A1 (0.48) | PIM1PTGER4XDH | |
| SCHEMBL28626819 | 0.77 | ALDH1A1 (0.52) | PIM1DHODHFFAR1FFAR4 | |
| SCHEMBL2744656 | 0.75 | ABL1 (0.51) | DHODHXDH | |
| SCHEMBL28923989 | 0.75 | SLC13A5 (0.48) | PIM1PTGER4DHODHFFAR1FFAR4 | |
| SCHEMBL29742871 | 0.75 | SLC13A5 (0.48) | PIM1PTGER4DHODHFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376091-A1 | THIADIAZOLEAMIDE DERIVATIVES AND THEIR APPLICATIONS | ZHEJIANG UNIVERSITY (CN) | 2024-11-14 | — | — | US | disclosed |
| CN-113444081-B | Thiadiazole carboxamide compounds and application thereof | 浙江大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113444081-A | Thiadiazole amide compound and application thereof | 浙江大学 | 2021-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240376091-A1 | THIADIAZOLEAMIDE DERIVATIVES AND THEIR APPLICATIONS | AR, GPER1, CYP19A1 | PIM1 2030/4885PTGER4 320/4885DHODH 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.