Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 11/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29742939 | 1.00 | PTGER4 (0.54) | PTGER4DRD1THRATHRBRXRA | |
| SCHEMBL29742884 | 0.86 | PIM1 (0.53) | PTGER4THRATHRB | |
| SCHEMBL28626376 | 0.86 | PIM1 (0.53) | PTGER4THRATHRB | |
| SCHEMBL29742912 | 0.85 | PTGER4 (0.61) | PTGER4MAPTGAPDH | |
| SCHEMBL28641494 | 0.76 | ALDH1A1 (0.53) | PTGER4DRD1RXRARXRBTAS2R14 | |
| SCHEMBL31223864 | 0.76 | ALDH1A1 (0.53) | PTGER4DRD1RXRARXRBTAS2R14 | |
| SCHEMBL28636888 | 0.76 | ALDH1A1 (0.48) | PTGER4 | |
| SCHEMBL29742860 | 0.76 | ALDH1A1 (0.48) | PTGER4 | |
| SCHEMBL29742877 | 0.74 | DRD1 (0.50) | PTGER4DRD1THRATHRBRXRA | |
| SCHEMBL28641731 | 0.74 | DRD1 (0.50) | PTGER4DRD1THRATHRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444081-B | Thiadiazole carboxamide compounds and application thereof | 浙江大学 | 2022-07-05 | — | — | CN | disclosed |
| CN-113444081-A | Thiadiazole amide compound and application thereof | 浙江大学 | 2021-09-28 | — | — | CN | disclosed |