Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CALML3 | P27482 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3553152 | 0.87 | RIPK1 (0.36) | KDM4ERIPK1POLBHTT | |
| SCHEMBL28626441 | 0.86 | KDM4E (0.32) | KDM4E | |
| SCHEMBL23645378 | 0.85 | RIPK1 (0.34) | KDM4ERIPK1POLBPLATHTT | |
| SCHEMBL23645415 | 0.81 | KMT2A (0.38) | KDM4EPOLB | |
| SCHEMBL23652648 | 0.80 | KMO (0.32) | — | |
| SCHEMBL23645451 | 0.80 | KMO (0.32) | RIPK1 | |
| SCHEMBL23652755 | 0.80 | KDM4E (0.34) | KDM4EPOLB | |
| SCHEMBL23652816 | 0.79 | DAO (0.33) | — | |
| SCHEMBL23645426 | 0.78 | KDM4E (0.35) | KDM4EPOLB | |
| SCHEMBL23653011 | 0.78 | KDM4E (0.33) | KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-A | Novel heteroatom aromatic amide derivative and drug containing the same | 科研制药株式会社 | 2021-04-20 | — | — | CN | disclosed |