Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.64 |
| ▸ | CA1 | P00915 | 6/20 | 0.63 |
| ▸ | CA2 | P00918 | 6/20 | 0.63 |
| ▸ | CA9 | Q16790 | 6/20 | 0.63 |
| ▸ | CA5A | P35218 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA3 | P07451 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14066807 | 0.89 | TSHR (0.64) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL4881844 | 0.87 | TSHR (0.62) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL20565451 | 0.86 | TSHR (0.60) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL10913128 | 0.86 | CA1 (0.55) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL5599951 | 0.85 | TSHR (0.89) | TSHRALDH1A1TDP1L3MBTL1TP53 | |
| SCHEMBL2809758 | 0.85 | TSHR (0.89) | TSHRALDH1A1TDP1L3MBTL1TP53 | |
| SCHEMBL8436890 | 0.84 | ALDH1A1 (0.67) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL11041492 | 0.81 | TSHR (0.70) | TSHRALDH1A1TDP1L3MBTL1TP53 | |
| SCHEMBL30748712 | 0.80 | CA1 (0.68) | TSHRCA1CA2CA9CA5A | |
| SCHEMBL8900471 | 0.80 | TSHR (0.80) | TSHRCA1CA2CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108883099-B | Thiazolidinone compounds and use thereof | 石全 | 2021-09-28 | — | — | CN | disclosed |