Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.61 |
| ▸ | AR | P10275 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | CBR1 | P16152 | 3/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636450 | 0.91 | POLB (0.53) | AKR1C3ARMAPTTP53MAOA | |
| SCHEMBL28626506 | 0.89 | AKR1C3 (0.60) | AKR1C3ARMAPTTP53MAOA | |
| SCHEMBL28630607 | 0.88 | MAPT (0.74) | MAPTTP53MEN1POLBKMT2A | |
| SCHEMBL28621873 | 0.81 | HSD17B1 (0.48) | AKR1C3ARMAPTTP53MAOA | |
| SCHEMBL28621586 | 0.81 | POLB (0.53) | AKR1C3ARMAPTTP53MAOA | |
| SCHEMBL28625763 | 0.80 | MAPT (0.62) | MAPTTP53MEN1POLBKMT2A | |
| SCHEMBL28641067 | 0.77 | MAPT (0.76) | MAPTTP53MEN1POLBKMT2A | |
| SCHEMBL28636610 | 0.76 | AKR1C3 (0.52) | AKR1C3ARMAPTTP53MAOA | |
| SCHEMBL3880564 | 0.75 | MAPT (0.77) | MAPTTP53MEN1POLBKMT2A | |
| SCHEMBL28865516 | 0.74 | MAOA (0.68) | AKR1C3MAPTMAOAMAOBAKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108715589-B | Coumarin derivative used as caspase-3 activator and application thereof | 华侨大学 | 2021-04-20 | — | — | CN | disclosed |