Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TACR3 | P29371 | 5/20 | 0.62 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | ACACA | Q13085 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 3/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626532 | 0.82 | DHODH (0.60) | KDM4ESMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL28617226 | 0.82 | ACP1 (0.57) | KDM4ESMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL29687349 | 0.82 | ACP1 (0.57) | KDM4ESMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL10263305 | 0.81 | KDM4E (0.73) | KDM4ESMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL28619856 | 0.81 | ACHE (0.56) | KDM4ESMN1; SMN2TACR3DHODHACACA | |
| SCHEMBL30064616 | 0.80 | KDM4E (0.75) | KDM4ESMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL28350370 | 0.80 | KDM4E (0.75) | KDM4ESMN1; SMN2MEN1KMT2ATACR3 | |
| SCHEMBL28622149 | 0.79 | MAPK1 (0.56) | KDM4ESMN1; SMN2MEN1KMT2APLA2G2A | |
| SCHEMBL28623574 | 0.79 | DHODH (0.54) | MEN1KMT2ATACR3PLA2G2AALDH1A1 | |
| SCHEMBL13757621 | 0.79 | SMN1; SMN2 (1.00) | KDM4ESMN1; SMN2MEN1KMT2ATACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277978-B | Preparation method of 2, 4-disubstituted quinoline compound | 河南师范大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113277978-A | Preparation method of 2, 4-disubstituted quinoline compound | 河南师范大学 | 2021-08-20 | — | — | CN | disclosed |