Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CPT2 | P23786 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | MVD | P53602 | 1/20 | 0.36 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | BHMT | Q93088 | 3/20 | 0.34 |
| ▸ | TPI1 | P60174 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104241 | 0.93 | FFAR1 (0.42) | FFAR1CPT2TDP1KDM4EHMGCR | |
| SCHEMBL5974079 | 0.82 | LPAR3 (0.39) | TDP1PGK1PGK2TPI1S1PR4 | |
| SCHEMBL3040965 | 0.82 | FFAR1 (0.53) | FFAR1CPT2TDP1KDM4EMVD | |
| SCHEMBL13103982 | 0.81 | FFAR1 (0.35) | FFAR1CPT2TDP1KDM4EHMGCR | |
| SCHEMBL1978883 | 0.79 | KDM4E (0.39) | FFAR1CPT2TDP1KDM4EHMGCR | |
| SCHEMBL25833481 | 0.79 | TPI1 (0.38) | TPI1DGAT1S1PR4S1PR1S1PR3 | |
| SCHEMBL7158770 | 0.78 | LPAR3 (0.41) | S1PR4S1PR1S1PR3S1PR5LPAR3 | |
| SCHEMBL13104409 | 0.76 | KDM4E (0.41) | FFAR1CPT2TDP1KDM4EHMGCR | |
| SCHEMBL11606163 | 0.76 | LPAR3 (0.40) | S1PR4S1PR1S1PR3S1PR5LPAR3 | |
| SCHEMBL13104247 | 0.76 | LPAR3 (0.35) | TSHRPGK1PGK2TPI1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423685-A | Prodrug modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-09-21 | — | — | CN | disclosed |