Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986652 | 0.76 | LMNA (0.53) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL28587704 | 0.75 | NPC1 (0.47) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14433861 | 0.71 | MEN1 (0.64) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL19986508 | 0.67 | LMNA (0.57) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL19986655 | 0.65 | BLM (0.42) | LMNATSHRRAB9A | |
| SCHEMBL31308946 | 0.64 | LMNA (1.00) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL12064759 | 0.63 | SLC2A1 (0.73) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL19986453 | 0.63 | LMNA (0.67) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL31309231 | 0.62 | MEN1 (0.78) | LMNAMEN1KMT2AMAPTTSHR | |
| SCHEMBL22094925 | 0.62 | LMNA (0.50) | LMNAMEN1KMT2AMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429341-A | Novel capsid protein assembly inhibitors | 正大天晴药业集团股份有限公司 | 2021-09-24 | — | — | CN | disclosed |