Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.38 |
| ▸ | CSF1R | P07333 | 5/20 | 0.38 |
| ▸ | LYN | P07948 | 5/20 | 0.38 |
| ▸ | KIT | P10721 | 5/20 | 0.38 |
| ▸ | SRC | P12931 | 5/20 | 0.38 |
| ▸ | FLT4 | P35916 | 5/20 | 0.38 |
| ▸ | FLT3 | P36888 | 5/20 | 0.38 |
| ▸ | BLK | P51451 | 5/20 | 0.38 |
| ▸ | FLT1 | P17948 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986509 | 0.85 | BLM (0.43) | BLMKDRTSHRRECQLGRM4 | |
| SCHEMBL19986652 | 0.81 | LMNA (0.53) | TSHRLMNARAB9A | |
| SCHEMBL19986584 | 0.76 | LMNA (0.64) | TSHRLMNARAB9A | |
| SCHEMBL19986554 | 0.74 | MEN1 (0.47) | BLMKDRRECQLGRM4LCK | |
| SCHEMBL19986457 | 0.71 | NPC1 (0.47) | BLMKDRTSHRGRM4EPHX2 | |
| SCHEMBL19986508 | 0.69 | LMNA (0.57) | TSHRLMNARAB9A | |
| SCHEMBL19986694 | 0.68 | NAMPT (0.41) | BLMKDRGRM4NAMPTUSP2 | |
| SCHEMBL19986713 | 0.68 | KCNJ6 (0.39) | BLMKDRGRM4LCKCSF1R | |
| SCHEMBL19986607 | 0.68 | NAMPT (0.41) | BLMKDRGRM4NAMPTUSP2 | |
| SCHEMBL19986668 | 0.68 | KCNJ6 (0.39) | BLMKDRGRM4LCKCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |