Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611606 | 0.88 | KDM4E (0.58) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL28611642 | 0.83 | KDM4E (0.54) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL10516279 | 0.76 | ADORA3 (0.57) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL13648979 | 0.75 | TP53 (0.62) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL28623634 | 0.75 | KDM4E (0.63) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL28619628 | 0.75 | KDM4E (0.57) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL28920726 | 0.74 | KDM4E (0.56) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL28624211 | 0.73 | ABCG2 (0.58) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL10516095 | 0.73 | ADORA3 (0.54) | KDM4ECYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL4649956 | 0.73 | KDM4E (0.80) | KDM4ECYP3A4HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301959-A | Substituted chromen-4-ones for the treatment and prevention of hepatitis B virus infection | 豪夫迈·罗氏有限公司 | 2021-08-24 | — | — | CN | disclosed |