Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630310 | 0.91 | LMNA (0.61) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL3848743 | 0.90 | ALDH1A1 (0.58) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL28923361 | 0.90 | POLB (0.56) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL3848741 | 0.90 | ALDH1A1 (0.58) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL7316058 | 0.90 | NPC1 (0.55) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL7316045 | 0.90 | NPC1 (0.55) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL28627339 | 0.89 | MEN1 (0.55) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL15967748 | 0.88 | NPC1 (0.57) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL15967749 | 0.88 | NPC1 (0.57) | NPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL28625318 | 0.87 | KMT2A (0.51) | NPC1LMNANPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641878-B | DIPROVOCIM: effective TLR agonist | 斯克里普斯研究学院 | 2021-09-14 | — | — | CN | disclosed |