Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627478 | 1.00 | FBP1 (0.49) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL15056165 | 0.89 | FBP1 (0.50) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL15056166 | 0.89 | FBP1 (0.50) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL29149940 | 0.79 | FBP1 (0.53) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL30259520 | 0.79 | FBP1 (0.53) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL20177880 | 0.79 | FBP1 (0.53) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL2077056 | 0.78 | FBP1 (0.56) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL2077055 | 0.78 | FBP1 (0.56) | FBP1ALDH1A1MAPTALOX12HTT | |
| SCHEMBL29193278 | 0.78 | FBP1 (0.53) | FBP1ALDH1A1MAPTAPP | |
| SCHEMBL29193282 | 0.78 | FBP1 (0.53) | FBP1ALDH1A1MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302185-B | Benzofuran-6-carboxamide derivatives, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-113302185-A | Benzofuran-6-carboxamide derivatives, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2021-08-24 | — | — | CN | disclosed |