Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL28627503

CCCCC(=O)O.OC(=S)c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.58
CES1 P23141 4/20 0.58
HDAC11 Q96DB2 6/20 0.52
HDAC3 O15379 1/20 0.52
HDAC4 P56524 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC10 Q969S8 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
HDAC9 Q9UKV0 1/20 0.52
HDAC5 Q9UQL6 1/20 0.52
PTGS2 P35354 1/20 0.50
AKR1B1 P15121 1/20 0.48
ALDH1A1 P00352 3/20 0.47
NR4A2 P43354 1/20 0.47
GPR84 Q9NQS5 6/20 0.47
PPARG P37231 6/20 0.47
PPARD Q03181 6/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valeric Acid SCHEMBL27903119 0.86 CES2 (0.54) CES2CES1HDAC11HDAC3HDAC4
Benzoic Acid SCHEMBL5787758 0.85 CES2 (0.61) CES2CES1HDAC11HDAC3HDAC4
Thiobenzoic Acid SCHEMBL28030107 0.82 CES2 (0.53) CES2CES1PTGS2ESR1
Benzamide SCHEMBL29027531 0.81 TSHR (0.59) CES2CES1HDAC11HDAC3HDAC4
Valeric Acid SCHEMBL28472481 0.80 MMP2 (0.44) HDAC11AKR1B1ALDH1A1GPR84PPARG
Biphenyl SCHEMBL27377379 0.80 AKR1B1 (0.56) CES2CES1HDAC11HDAC3HDAC4
Valeric Acid SCHEMBL1674731 0.79 AKR1B1 (0.74) HDAC11HDAC3HDAC1HDAC2HDAC8
Benzoic Acid SCHEMBL10947409 0.79 CES2 (0.62) CES2CES1HDAC11HDAC3HDAC4
Thiobenzoic Acid SCHEMBL579975 0.79 CES2 (0.53) CES2CES1HDAC11HDAC3HDAC4
Valeric Acid SCHEMBL28606633 0.79 HDAC3 (0.58) CES2CES1HDAC11HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112694618-B Linear poly-antibacterial peptide and preparation method and application thereof 江苏大学 2022-04-26 CN claimed
CN-112694618-A Linear poly-antibacterial peptide and preparation method and application thereof 江苏大学 2021-04-23 CN claimed
CN-112694618-B Linear poly-antibacterial peptide and preparation method and application thereof 江苏大学 2022-04-26 CN disclosed
CN-112694618-A Linear poly-antibacterial peptide and preparation method and application thereof 江苏大学 2021-04-23 CN disclosed