SCHEMBL28627656

SCHEMBL28627656

Cc1ccc(S(=O)(=O)NC(CCc2cccc(F)c2)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
KMT2A Q03164 2/20 0.47
UTS2R Q9UKP6 1/20 0.46
EEF2K O00418 2/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CYP1A2 P05177 3/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
ATM Q13315 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
TP53 P04637 3/20 0.44
MAPT P10636 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
THRB P10828 1/20 0.44
CYP3A4 P08684 2/20 0.44
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
CYP19A1 P11511 1/20 0.43
ADAMTS4 O75173 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28620694 0.88 ALDH1A1 (0.71) ALDH1A1KMT2AUTS2RCA2CA7
SCHEMBL28922034 0.87 ALDH1A1 (0.63) ALDH1A1KMT2AUTS2RCA2CA7
SCHEMBL28631121 0.86 ALDH1A1 (0.62) ALDH1A1KMT2AUTS2REEF2KCA2
SCHEMBL28856633 0.81 ALDH1A1 (0.56) ALDH1A1KMT2AEEF2KCA2CA7
SCHEMBL28617906 0.81 ALDH1A1 (0.58) ALDH1A1KMT2ACA2CA7CYP1A2
SCHEMBL29981529 0.81 ALDH1A1 (0.58) ALDH1A1KMT2ACA2CA7CYP1A2
SCHEMBL28621232 0.80 EEF2K (0.61) ALDH1A1KMT2AUTS2REEF2KCA2
SCHEMBL28616437 0.80 ALDH1A1 (0.59) ALDH1A1UTS2REEF2KCA2CA7
SCHEMBL16300320 0.78 CA2 (0.63) ALDH1A1KMT2AUTS2RCA2CA7
SCHEMBL30801085 0.78 CA2 (0.63) ALDH1A1KMT2AUTS2RCA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113105374-B Method for synthesizing alkylamine derivative 西湖大学 2022-10-11 CN disclosed
CN-113105374-A Method for synthesizing alkylamine derivative 西湖大学 2021-07-13 CN disclosed