Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22218417 | 0.90 | P2RY12 (0.40) | HDAC1HDAC8HDAC6HDAC5KMT2A | |
| SCHEMBL22218312 | 0.89 | HDAC1 (0.50) | HDAC1HDAC8HDAC6HDAC5KMT2A | |
| SCHEMBL20236895 | 0.89 | GAA (0.40) | HDAC1HDAC8HDAC6HDAC5KMT2A | |
| SCHEMBL28634587 | 0.89 | HDAC1 (0.43) | HDAC1HDAC8HDAC6HDAC5GABRA5 | |
| SCHEMBL20236627 | 0.89 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5KMT2A | |
| SCHEMBL28647079 | 0.89 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5KMT2A | |
| SCHEMBL28627863 | 0.89 | ALDH1A1 (0.42) | KMT2AGABRA5TSHRGAAMAPT | |
| SCHEMBL22218214 | 0.88 | KMT2A (0.41) | HDAC1HDAC8HDAC6HDAC5KMT2A | |
| SCHEMBL22218212 | 0.88 | GABRA5 (0.41) | HDAC1HDAC8HDAC6HDAC5KMT2A | |
| Hydrochloric Acid SCHEMBL20236412 | 0.88 | HDAC1 (0.39) | HDAC1HDAC8HDAC6HDAC5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137518-B | 1,3, 4-oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same | 株式会社钟根堂 | 2021-08-31 | — | — | CN | disclosed |