SCHEMBL2862799

SCHEMBL2862799

Cc1cc(C(C)(C)C)ccc1[O]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
ALDH1A1 P00352 5/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NPC1 O15118 1/20 0.42
PLA2G1B P04054 1/20 0.42
NFKB1 P19838 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
POLB P06746 1/20 0.41
GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4396817 0.83 TSHR (0.44) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL3415979 0.78 TSHR (0.44) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL3028480 0.78 PDE2A (0.42) ALDH1A1HPGDHSD17B10MEN1KMT2A
SCHEMBL585667 0.78 ALDH1A1 (0.43) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL29498849 0.76 TSHR (0.52) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL2009857 0.76 TSHR (0.52) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL9912479 0.75 TSHR (0.46) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL8467570 0.74 ALDH1A1 (0.50) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL30010382 0.73 ALDH1A1 (0.52) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL348347 0.73 ALDH1A1 (0.52) TSHRALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180057685-A1 FLAME-RETARDANT RESIN COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-8653176-B2 Thermally conductive material and thermally conductive sheet molded from the thermally conductive material ASAHI KASEI E-MATERIALS CORPORATION (JP) 2014-02-18 US disclosed
US-8562873-B2 Flame retarder composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-10-22 US disclosed
US-7759418-B2 Flame retardant resin composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-07-20 US disclosed
US-20100012884-A1 THERMALLY CONDUCTIVE MATERIAL AND THERMALLY CONDUCTIVE SHEET MOLDED FROM THE THERMALLY CONDUCTIVE MATERIAL ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-01-21 US disclosed
US-20080051495-A1 Flame Retardant Resin Composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2008-02-28 US disclosed
US-20070040154-A1 Flame retarder composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-02-22 US disclosed
US-7091266-B2 Flame retardant composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2006-08-15 US disclosed
US-7060744-B2 Phosphazene composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-06-13 US disclosed
US-20050228087-A1 Flame retardant composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2005-10-13 US disclosed
US-20040039134-A1 Phosphazene composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2004-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057685-A1 FLAME-RETARDANT RESIN COMPOSITION PRPF4, RPL4, PSMB4 TSHR 3139/4885ALDH1A1 1366/4885HPGD 3479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.