Sugi Predict

Sugi Predict / Compounds / SCHEMBL585667

SCHEMBL585667

SCHEMBL585667

CC(C)(C)c1ccc([O])c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ HPGD P15428 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ NPC1 O15118 1/20 0.41
▸ PLA2G1B P04054 1/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ CASP3 P42574 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ NFKB2 Q00653 1/20 0.41
▸ RELA Q04206 1/20 0.41
▸ SENP8 Q96LD8 1/20 0.41
▸ SENP7 Q9BQF6 1/20 0.41
▸ SENP6 Q9GZR1 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ ATG4B Q9Y4P1 1/20 0.41
▸ MEN1 O00255 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3415979 0.81 TSHR (0.44) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL11042250 0.78 ALDH1A1 (0.35) ALDH1A1TDP1ALOX15HSD17B10MAPT
SCHEMBL2862799 0.78 TSHR (0.46) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL779415 0.77 ALDH1A1 (0.48) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL29630132 0.77 ALDH1A1 (0.48) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL396008 0.76 ALDH1A1 (0.44) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL29394427 0.76 ALDH1A1 (0.39) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL2357462 0.75 ALDH1A1 (0.48) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL29763177 0.75 ALDH1A1 (0.48) ALDH1A1TDP1HPGDALOX15HSD17B10
SCHEMBL2582081 0.74 CYP2C19 (0.47) ALDH1A1TDP1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116726996-A Catalyst for isomerization of branched unsaturated fatty nitrile, preparation method and application thereof 北京旭阳科技有限公司 2023-09-12 — — CN claimed
CN-116693573-A Column arene bisphosphite ligand, and preparation method and application thereof 北京旭阳科技有限公司 2023-09-05 — — CN claimed
CN-107513217-B A kind of polypropylene-base polymer gradient functional material and preparation method thereof 四川大学 2019-11-22 — — CN claimed
EP-3559087-A1 METHOD FOR LOWERING THE CRYSTALLIZATION TEMPERATURE OF SEMICRYSTALLINE POLYAMIDES, POLYAMIDE MOLDING COMPOUND PRODUCED THEREBY, AND USE OF ORGANIC PHOSPHORUS COMPOUNDS TO LOWER THE CRYSTALLIZATION TEMPERATURE Fraunhofer Gesellschaft zur Förderung der Angewand (DE) 2019-10-30 — — EP claimed
CN-103627069-B High-transparency polyethylene film master batch 中国石油天然气股份有限公司 2016-06-08 — — CN claimed
CN-105633328-A Polypropylene porous membrane for lithium-ion battery and preparation method of polypropylene porous membrane UNIV HENAN NORMAL 2016-06-01 — — CN claimed
CN-103627070-B Low-haze polyethylene film resin composition PETROCHINA COMPANY LIMITED (CN) 2016-04-06 — — CN claimed
CN-105367924-A Granulated plastic additive and preparation method and application thereof PETROCHINA CO LTD 2016-03-02 — — CN claimed
CN-103627062-B High-transparency polyolefin film master batch PETROCHINA COMPANY LIMITED (CN) 2016-01-20 — — CN claimed
CN-104266143-B The anti-explosion LED electricity-saving lamp used under a kind of adverse circumstances PAN FANFENG (CN) 2015-10-28 — — CN claimed
US-6613943-B2 Intermediates for 4-substituted-2,5-diaminophenol derivatives as phenolic cyan couplers for color photography; deblocking the 2-acyl group by hydrolysis EASTMAN KODAK COMPANY 2003-09-02 — — US claimed
US-20030109716-A1 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM EASTMAN KODAK COMPANY 2003-06-12 — — US claimed
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2003-06-12 — — US claimed
EP-1316550-A1 6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them EASTMAN KODAK COMPANY (US) 2003-06-04 — — EP claimed
EP-1316544-A1 5-acylamino-2-amino-4-substituted-phenol compounds and method of using them EASTMAN KODAK COMPANY (US) 2003-06-04 — — EP claimed
US-20030078347-A1 Triazine compounds, polymers comprising triazine structural units, and method GENERAL ELECTRIC COMPANY 2003-04-24 — — US claimed
WO-2003024939-A2 TRIAZINE COMPOUNDS POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS GENERAL ELECTRIC COMPANY (US) 2003-03-27 — — WO claimed
US-6525219-B1 Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation EASTMAN KODAK COMPANY 2003-02-25 — — US claimed
US-6482953-B1 2-benzyloxy-4-nitro-5-substituted-acylanilide compounds and method of using them EASTMAN KODAK COMPANY 2002-11-19 — — US claimed
US-6476202-B1 5-acylamino-2-arylazo, nitro, or nitroso-4-substituted-phenol compounds and method of using them EASTMAN KODAK COMPANY 2002-11-05 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109753-A1 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them CBR3, AADAC, HAAO ALDH1A1 404/4885TDP1 2540/4885HPGD 811/4885
US-20030109716-A1 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM AADAT, AAAS, ANXA7 ALDH1A1 795/4885TDP1 1569/4885HPGD 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.