SCHEMBL2862809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4333969	0.87	SMN1; SMN2 (0.51)	RAB9ARXFP1ALDH1A1SMN1; SMN2TSHR
	SCHEMBL4332582	0.82	L3MBTL1 (0.51)	RAB9ARXFP1ALDH1A1SMN1; SMN2TSHR
	SCHEMBL6678602	0.78	FLT3 (0.59)	ALDH1A1SMN1; SMN2TSHRLMNAUSP2
	SCHEMBL2865232	0.76	MAPK1 (0.53)	RAB9ASMN1; SMN2LMNANAMPTMAPK1
	SCHEMBL2860415	0.75	MAPK10 (0.54)	MAPK1MAPK10
	SCHEMBL30068415	0.73	HTR1A (0.59)	RAB9ARXFP1ALDH1A1SMN1; SMN2TSHR
	SCHEMBL10195551	0.72	NAMPT (0.48)	RAB9ARXFP1ALDH1A1SMN1; SMN2TSHR
	SCHEMBL6444431	0.72	RCE1 (0.51)	ALDH1A1SMN1; SMN2TSHRLMNAHPGD
	SCHEMBL5380014	0.72	MAPK10 (0.56)	MAPK1MAPK10
	SCHEMBL5377524	0.71	MAPK10 (0.53)	KDM4EMAPK1MAPK10HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.