Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 17/20 | 0.41 |
| ▸ | PDE4A | P27815 | 10/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628145 | 1.00 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CSTING1 | |
| SCHEMBL21158117 | 0.87 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CSTING1 | |
| SCHEMBL28628473 | 0.87 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CSTING1 | |
| SCHEMBL28628474 | 0.87 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CSTING1 | |
| SCHEMBL21158773 | 0.81 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4CMAPK8 | |
| SCHEMBL21158094 | 0.79 | STING1 (0.36) | PDE4BSTING1 | |
| SCHEMBL19437548 | 0.78 | HTT (0.38) | STING1 | |
| SCHEMBL19437549 | 0.78 | HTT (0.38) | STING1 | |
| SCHEMBL21158910 | 0.74 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4CF2 | |
| SCHEMBL21643823 | 0.73 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016025-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-08-06 | — | — | CN | disclosed |