Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.48 |
| ▸ | PDE4A | P27815 | 9/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | F3 | P13726 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158773 | 0.94 | PDE4D (0.50) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158643 | 0.89 | STING1 (0.42) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158931 | 0.84 | PDE4D (0.35) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL28552449 | 0.79 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158926 | 0.79 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL21158654 | 0.78 | PARP15 (0.43) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL19437435 | 0.78 | ALDH1A1 (0.46) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158909 | 0.78 | IRAK4 (0.38) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158729 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL22121045 | 0.76 | TSHR (0.43) | PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019134707-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |