Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.50 |
| ▸ | PDE4A | P27815 | 10/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158910 | 0.94 | PDE4D (0.48) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158643 | 0.91 | STING1 (0.42) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL28552449 | 0.86 | PDE4D (0.47) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158931 | 0.82 | PDE4D (0.35) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL28628145 | 0.81 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CMAPK8 | |
| SCHEMBL28628148 | 0.81 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CMAPK8 | |
| SCHEMBL21158117 | 0.79 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CMAPK8 | |
| SCHEMBL21158909 | 0.78 | IRAK4 (0.38) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL28912725 | 0.78 | MAPT (0.44) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL21158926 | 0.77 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2019134707-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |