Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | LCAT | P04180 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.30 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28628307 | 1.00 | LMNA (0.38) | LMNAMAPTKIF11GRIK1GRIK2 | |
| SCHEMBL28629671 | 0.90 | LMNA (0.36) | LMNAMAPTGRIK1GRIK2CHRM4 | |
| SCHEMBL28629669 | 0.90 | LMNA (0.36) | LMNAMAPTGRIK1GRIK2CHRM4 | |
| SCHEMBL28629677 | 0.86 | CYP2D6 (0.36) | KIF11GRIK1GRIK2CYP2D6CA12 | |
| SCHEMBL18579427 | 0.86 | LMNA (0.34) | LMNAPDE10A | |
| SCHEMBL18579429 | 0.86 | LMNA (0.34) | LMNAPDE10A | |
| SCHEMBL28625054 | 0.85 | LMNA (0.37) | LMNAMAPTCYP2D6CHRM4PDE10A | |
| SCHEMBL18579478 | 0.84 | LMNA (0.47) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL18579481 | 0.84 | LMNA (0.47) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL18579195 | 0.81 | LMNA (0.39) | LMNAMAPTCHRM4PDE2AIP6K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025189-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-07-02 | — | — | CN | disclosed |