Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366218 | 0.94 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1CHRM1 | |
| SCHEMBL3951666 | 0.91 | — | — | |
| SCHEMBL21293507 | 0.78 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1CHRM1 | |
| SCHEMBL13992792 | 0.71 | ALDH1A1 (0.38) | OPRM1OPRD1OPRK1OPRL1CHRM1 | |
| SCHEMBL10048454 | 0.71 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1CHRM1 | |
| SCHEMBL13992800 | 0.70 | SLC6A4 (0.38) | OPRM1OPRD1OPRK1OPRL1CHRM1 | |
| SCHEMBL2141410 | 0.68 | — | — | |
| SCHEMBL28578419 | 0.68 | CHRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1CHRM1 | |
| SCHEMBL8519318 | 0.67 | CHRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1CHRM1 | |
| SCHEMBL7414855 | 0.67 | AKR1C1 (0.42) | OPRM1OPRD1OPRK1OPRL1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218227-B | Method for preparing aryl ketone derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-109232448-B | (E) -chloropropylketene/olefine aldehyde triazole compound and synthesis method thereof | 陕西师范大学 | 2021-09-21 | — | — | CN | disclosed |