SCHEMBL28628819

SCHEMBL28628819

NC(=O)N[SiH3].c1cc2ccc1-2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 9/20 0.46
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PEPD P12955 1/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA14 Q9ULX7 1/20 0.37
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 2/20 0.35
NFKB1 P19838 2/20 0.35
CYP1A2 P05177 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
THPO P40225 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134446 0.80
SCHEMBL28337914 0.80 LMNA (0.50) CA2CA9ALDH1A1TSHRNFKB1
Fluoride SCHEMBL28057803 0.77
Urea SCHEMBL8378844 0.77 TDP1 (0.50) KIF11HTTSMN1; SMN2L3MBTL1CA2
SCHEMBL11416941 0.77
Water SCHEMBL28511567 0.77
Ammonia Solution, Strong SCHEMBL28127963 0.77
SCHEMBL27977843 0.77 KIF11 (0.46) KIF11HTTSMN1; SMN2L3MBTL1PEPD
Acetamide SCHEMBL1279079 0.71 LMNA (0.57) KIF11HTTSMN1; SMN2L3MBTL1CA2
SCHEMBL27898572 0.71 KIF11 (0.41) KIF11HTTSMN1; SMN2L3MBTL1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372378-B Preparation process of phenylureido silane coupling agent 安徽沸点新材料有限公司 2023-11-21 CN disclosed
CN-113372378-B Preparation process of phenylureido silane coupling agent 安徽沸点新材料有限公司 2023-11-21 CN disclosed
CN-113372378-A Preparation process of phenylureido silane coupling agent 安徽沸点新材料有限公司 2021-09-10 CN disclosed