Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421711 | 0.79 | ALDH1A1 (0.49) | L3MBTL1MAPTHPGDCYP1A2CYP2C19 | |
| SCHEMBL134595 | 0.77 | LMNA (0.48) | L3MBTL1MAPTHPGDCYP2C19CYP2C9 | |
| SCHEMBL4897444 | 0.77 | LMNA (0.48) | L3MBTL1MAPTHPGDCYP2C19CYP2C9 | |
| SCHEMBL29444902 | 0.77 | LMNA (0.48) | L3MBTL1MAPTHPGDCYP2C19CYP2C9 | |
| SCHEMBL2094937 | 0.75 | MEN1 (0.58) | L3MBTL1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10358890 | 0.74 | TDP1 (0.42) | L3MBTL1NPC1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL11069560 | 0.73 | ALDH1A1 (0.44) | L3MBTL1MAPTHPGDCYP1A2CYP3A4 | |
| Pentachlorophenol SCHEMBL9847209 | 0.70 | ALDH1A1 (0.42) | L3MBTL1MAPTHPGDCYP1A2CYP3A4 | |
| SCHEMBL11069544 | 0.70 | CSNK2A1 (0.37) | L3MBTL1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8841078 | 0.70 | SLC6A2 (0.45) | MAPTHPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997757-B | Isocyanate-functional silicone-polyether copolymers, silicone-polyether-urethane copolymers formed therewith, sealants including the same, and related methods | 美国陶氏有机硅公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-113195507-A | Multifunctional organosilicon compounds and related methods, compounds, and compositions | 美国陶氏有机硅公司 | 2021-07-30 | — | — | CN | disclosed |