Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29586304 | 0.91 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL9147 | 0.91 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL14167546 | 0.86 | CNR2 (0.53) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL3643028 | 0.86 | UBE2T (0.43) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL219142 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL29092810 | 0.80 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL28377534 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL16967457 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL29377204 | 0.77 | UBE2T (0.51) | ALDH1A1HSD17B10HPGDMAPTKDM4E | |
| SCHEMBL676085 | 0.77 | UBE2T (0.51) | ALDH1A1HSD17B10HPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195490-A | Triazolopyridin-3-one or salt thereof and pharmaceutical composition comprising same | 柳韩洋行 | 2021-07-30 | — | — | CN | disclosed |