Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.67 |
| ▸ | BCHE | P06276 | 9/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.65 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.65 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894611 | 1.00 | ACHE (0.67) | ACHEBCHEMAOBALDH1A1MAPT | |
| SCHEMBL15972679 | 0.89 | MAOB (0.67) | ACHEBCHEMAOBALDH1A1MAPT | |
| SCHEMBL15971607 | 0.87 | MAOB (0.65) | ACHEBCHEMAOBALDH1A1MAPT | |
| SCHEMBL15973862 | 0.87 | MAOB (0.65) | ACHEBCHEMAOBALDH1A1MAPT | |
| SCHEMBL7758792 | 0.87 | KDM4E (0.60) | ACHEBCHEMAOBALDH1A1MAPT | |
| SCHEMBL29894593 | 0.86 | KDM4E (0.76) | ACHEBCHEALDH1A1MAPTKDM4E | |
| SCHEMBL28627763 | 0.86 | KDM4E (0.76) | ACHEBCHEALDH1A1MAPTKDM4E | |
| SCHEMBL15971787 | 0.86 | MAOB (0.64) | ACHEBCHEMAOBALDH1A1MAPT | |
| SCHEMBL15973644 | 0.86 | MAOB (0.67) | ACHEBCHEMAOBALDH1A1MAPT | |
| SCHEMBL15973648 | 0.86 | MAOB (0.67) | ACHEBCHEMAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336735-B | Urolithin compound, preparation method, pharmaceutical composition and application | 常州大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-113336735-A | Urolithin compound, preparation method, pharmaceutical composition and application | 常州大学 | 2021-09-03 | — | — | CN | disclosed |