Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320577 | 0.93 | NAMPT (0.52) | NAMPTIMPDH2ROCK2ROCK1ADORA3 | |
| SCHEMBL30943224 | 0.82 | NAMPT (0.84) | NAMPTIMPDH2ROCK2ROCK1 | |
| SCHEMBL24042554 | 0.82 | NAMPT (0.84) | NAMPTIMPDH2ROCK2ROCK1 | |
| SCHEMBL30943229 | 0.82 | NAMPT (0.75) | NAMPTIMPDH2ROCK2ROCK1 | |
| SCHEMBL23320533 | 0.82 | NAMPT (0.75) | NAMPTIMPDH2ROCK2ROCK1 | |
| SCHEMBL23320444 | 0.76 | NAMPT (1.00) | NAMPTPRMT3RAB9A | |
| SCHEMBL24042588 | 0.74 | NAMPT (0.77) | NAMPTROCK2ROCK1RAB9A | |
| SCHEMBL23320389 | 0.73 | NAMPT (1.00) | NAMPTIMPDH2ROCK2ROCK1ADORA3 | |
| SCHEMBL23320417 | 0.69 | NAMPT (0.75) | NAMPT | |
| SCHEMBL30943213 | 0.69 | NAMPT (0.75) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | claimed |
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |