Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24042554 | 1.00 | NAMPT (0.84) | NAMPTHTTROCK2ROCK1IMPDH2 | |
| SCHEMBL23320444 | 0.92 | NAMPT (1.00) | NAMPT | |
| SCHEMBL23320516 | 0.83 | NAMPT (0.82) | NAMPTROCK2ROCK1 | |
| SCHEMBL28629417 | 0.82 | NAMPT (0.58) | NAMPTROCK2ROCK1IMPDH2 | |
| SCHEMBL23320512 | 0.82 | NAMPT (0.74) | NAMPTHTTROCK2ROCK1IMPDH2 | |
| SCHEMBL24042607 | 0.80 | NAMPT (0.54) | NAMPT | |
| SCHEMBL28620099 | 0.79 | NAMPT (0.73) | NAMPT | |
| SCHEMBL23320577 | 0.78 | NAMPT (0.52) | NAMPTROCK2ROCK1IMPDH2 | |
| SCHEMBL23320429 | 0.75 | NAMPT (0.69) | NAMPTHTT | |
| SCHEMBL30943290 | 0.75 | NAMPT (0.69) | NAMPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |